Acute and subchronic dermal toxicity of nanosilver in guinea pig
نویسندگان
چکیده
منابع مشابه
Acute and subchronic dermal toxicity of nanosilver in guinea pig
Silver has been used as an antimicrobial agent for a long time in different forms, but silver nanoparticles (nanosilver) have recently been recognized as potent antimicrobial agents. Although nanosilver is finding diverse medical applications such as silver-based dressings and silver-coated medical devices, its dermal and systemic toxicity via dermal use has not yet been identified. In this stu...
متن کاملSub-chronic Dermal Toxicity of Silver Nanoparticles in Guinea Pig: Special Emphasis to Heart, Bone and Kidney Toxicities
Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...
متن کاملSub-chronic Dermal Toxicity of Silver Nanoparticles in Guinea Pig: Special Emphasis to Heart, Bone and Kidney Toxicities
Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...
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As a result of growing applications of manufactured nanoparticles, there is an increasing concern aboutpossible side effects of exposure to these materials on human and environment. Nanosilver (n-Ag) has foundwide use in medical applications including development of silver-based dressings and silver-coated medicaldevices. However, toxicity of these particles clue to their dermal use has not bee...
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Silver salts and nanosilver (NS) are the common antimicrobial used in the treatment of chronic wounds, so they are important to assess their dermal toxicity. Therefore, in this study, the possible dermal toxicity of NS particles and silver nitrate (AgNO3), was tested by determining the serum level of transforming growth factor-β1(TGF-β1) and study on of mouse skin tissue. In this stu...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2011
ISSN: 1178-2013
DOI: 10.2147/ijn.s17065